What medicine should I take after colon cancer surgery?
Postoperative drug treatment for colon cancer is a key link in the recovery process. A reasonable drug regimen can effectively reduce the risk of recurrence, control complications, and improve the patient's quality of life. The following is a collection of structured data on topics related to postoperative medication for colon cancer that have been hotly debated across the Internet in the past 10 days for the reference of patients and their families.
1. Classification of commonly used drugs after colon cancer surgery
| drug type | Representative medicine | function | Medication cycle |
|---|---|---|---|
| chemotherapy drugs | Oxaliplatin, capecitabine | Kill remaining cancer cells | Usually 4-6 months |
| Targeted drugs | Bevacizumab, cetuximab | Precisely inhibit tumor growth | Determined based on genetic test results |
| immunomodulatory drugs | PD-1 inhibitors (such as pembrolizumab) | Activate immune system to fight cancer | Continuous monitoring of efficacy is required |
| auxiliary medicine | Probiotics, antiemetics | Ease treatment side effects | Discontinue use after symptoms subside |
2. Basis for selecting postoperative medication regimen
According to the latest clinical guidelines, postoperative medication for colon cancer needs to take into consideration the following factors:
| Evaluation indicators | Medication recommendations |
|---|---|
| Tumor staging (TNM staging) | Chemotherapy is necessary for stage III, and chemotherapy should be considered for high-risk stage II. |
| Microsatellite instability (MSI) | MSI-H patients may be exempt from chemotherapy |
| RAS/BRAF gene status | Decide on targeted drug selection |
| Patient performance status (PS score) | Adjust medication intensity |
3. Recent hot and controversial topics
1."Oxaliplatin Neurotoxicity" Management Plan: Latest study shows alpha-lipoic acid may prevent peripheral neuropathy
2.Controversy over auxiliary treatment with traditional Chinese medicine: The National Cancer Center reminds us to be wary of interactions between traditional Chinese medicine and chemotherapy drugs
3.Immunotherapy moving forward: New evidence obtained on the use of PD-1 inhibitors as postoperative adjuvant therapy for patients with dMMR type
4. Precautions during medication
| Time node | Monitoring items | early warning sign |
|---|---|---|
| during chemotherapy | Blood routine, liver and kidney function | Neutrophils <1.5×10⁹/L |
| Targeted therapy period | blood pressure, urine protein | Blood pressure＞140/90mmHg |
| Follow-up after discontinuation of medication | Tumor markers, imaging | CEA continues to rise |
5. Nutritional support and drug synergy
1.Vitamin supplement principles: Avoid large doses of vitamin C from affecting the effect of chemotherapy
2.protein intake: 1.2-1.5g/kg body weight daily to promote albumin recovery
3.dietary fiber: Gradually increase intake and improve intestinal flora
6. Answers to Frequently Asked Questions by Patients
Q: Are painkillers addictive?
A: The risk of addiction to short-term standardized use of opioid analgesics is <1%, and pain control is more important.
Q: When can I consider participating in a clinical trial?
A: Patients who fail standard treatments or are at high risk of relapse can seek clinical trial opportunities for new drugs.
Q: Can health products replace medicines?
A: All health products cannot replace regular anti-tumor treatment, so you need to be wary of false propaganda.
Note: The specific medication plan needs to be formulated by an oncologist based on individual circumstances. This article is for reference only. If you experience any discomfort during medication, please seek medical advice promptly.
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